Lipid Zyme

Fatty deposits in the eye called Drusen are metabolic wastes that build up and can distort the vision, damage the macula, and lead to blindness… 

Retail $79.97 Your Price $69.97

More details:

The recommended dosage range is 1 to 2 capsules up to 3 times daily between meals, as guided and according to tolerance.

Each phthalate-free enteric vegicap of Lipid Zyme supplies:

Enzymes:

Quote: "Using systemic enzyme therapy or treatment with enzymes that affect the entire system also helps to inhibit the macular degeneration, augment blood circulation to the eye by means of disintegrating the cholesterol and fibrin accumulations, thereby enhancing the visual acuity or sharpness of vision."
(Emphasizes systemic oral enzymes' fibrinolytic and lipolytic actions to break down deposits like cholesterol/fibrin in drusen, improving ocular perfusion in AMD.)
Article Title: Enzyme Therapy
Publication: Herbs2000 (Clinical Herbal Guide)
Link: https://www.herbs2000.com/h_menu/t_enzyme.htm

Lipase (48,000 Units) 400 mg 

Lipase taken between meals in an enteric format acts as a systemic enzyme therapy to support mobilization of the fat component of Drusen deposits.

SBO (Soil-Based Organism): Neutral Protease (Bacillus licheniformis) (33,750 U) 100 mg 

Protease taken between meals in an enteric format acts as a systemic enzyme therapy to support mobilization of the protein component of Drusen deposits.

"Enteric-coated proteolytic enzyme preparations like Wobenzym and Phlogenzym are widely used for the so-called 'systemic enzyme therapy' both in humans and animals. Numerous publications reveal that oral proteolytic enzymes are able to stimulate directly the activity of immune competent cells as well as to increase efficiency of some of their products."
(Describes systemic immunostimulatory effects of enteric proteolytics, potentially aiding drusen clearance via enhanced phagocytosis and reduced inflammation in AMD.)
Article Title: Where do the immunostimulatory effects of oral proteolytic enzymes ('systemic enzyme therapy') come from? Microbial proteolysis as a possible starting point
Publication: Medical Hypotheses
Link: https://pubmed.ncbi.nlm.nih.gov/16870353/

Lipid Mobilizing Carotenoid:

Kelp: Fucoxanthin 85% (Laminaria spp.) 3.1 mg

Fucoxanthin, a marine carotenoid, has been studied for its antioxidant and anti-inflammatory properties in retinal pigment epithelial (RPE) cells, particularly in contexts involving lipid peroxidation and impaired phagocytosis—processes linked to drusen formation (extracellular lipid-rich deposits) in age-related macular degeneration (AMD). Below are the most relevant quotes from peer-reviewed literature, selected for their direct ties to lipid handling, phagocytosis in lipid-rich environments, and drusen inhibition via reduced amyloid-beta (Aβ) deposition (a component exacerbating drusen).

"Marked oxidative stress, inflammation, and phagocytosis disruption were evident in differentiated RPE cells following their exposure to visible light under a docosahexaenoic acid (DHA)-rich environment. Following pretreatment with fucoxanthin, however, the activated nuclear factor erythroid-derived-2-like 2 (Nrf2) signaling pathway was observed and, furthermore, when the fucoxanthin-pretreated RPE cells were irradiated with visible light, intracellular reactive oxygen species (ROS), malondialdehyde (MDA) levels and inflammation were obviously suppressed, while phagocytosis was significantly improved."

(This highlights fucoxanthin's enhancement of phagocytosis in lipid-rich (DHA, a polyunsaturated fatty acid) conditions, aiding clearance of lipid-laden debris akin to drusen precursors.)

Article Title: Fucoxanthin Pretreatment Ameliorates Visible Light-Induced Phagocytosis Disruption of RPE Cells under a Lipid-Rich Environment via the Nrf2 Pathway

Publication: Marine Drugs

Link: https://www.mdpi.com/1660-3397/20/1/15

"Due to their abundance of PUFAs [polyunsaturated fatty acids], lipid peroxidation of POSs [photoreceptor outer segments] occurs before being swallowed in the presence of light exposure. Given the close contact between RPE and POSs, this lipid peroxidation appears to be an important cause of visible light-induced damage to RPE cells. The results of this present study further confirmed that under the condition of visible light plus DHA exposure, obvious oxidative injury occurred in the RPE cells... [Fucoxanthin] can effectively inhibit oxidative stress and inflammation induced by visible light plus DHA in RPE cells."

(Emphasizes fucoxanthin's mitigation of lipid peroxidation in PUFA-rich settings, promoting lipid handling and reducing damage that contributes to drusen accumulation.)

Article Title: Fucoxanthin Pretreatment Ameliorates Visible Light-Induced Phagocytosis Disruption of RPE Cells under a Lipid-Rich Environment via the Nrf2 Pathway

Publication: Marine Drugs

Link: https://www.mdpi.com/1660-3397/20/1/15

"Our results show that the expression of Aβ and BACE1 decreased upon exposure to hydrogen peroxide... decreased expression of Aβ suggests it is related to the inhibition of drusen formation."
(Directly links fucoxanthin's reduction of Aβ (a drusen component) to potential inhibition of drusen, a key lipid deposit in early AMD.)
Article Title: Cytoprotective Potential of Fucoxanthin in Oxidative Stress-Induced Age-Related Macular Degeneration and Retinal Pigment Epithelial Cell Senescence In Vivo and In Vitro
Publication: Antioxidants (Basel)
Link: https://pmc.ncbi.nlm.nih.gov/articles/PMC7923087/

"An administration of fucoxanthin significantly inhibited ROS generation, reduced MDA concentrations and increased the mitochondrial metabolic rate in oxidative stress-induced RPE cell damage."
(MDA measures lipid peroxidation; this quote underscores fucoxanthin's role in breaking down oxidized lipids, relevant to mobilizing drusen-like deposits.)
Article Title: Cytoprotective Potential of Fucoxanthin in Oxidative Stress-Induced Age-Related Macular Degeneration and Retinal Pigment Epithelial Cell Senescence In Vivo and In Vitro
Publication: Antioxidants (Basel)
Link: https://pmc.ncbi.nlm.nih.gov/articles/PMC7923087/

"Pretreatment of fucoxanthin significantly suppresses oxidative stress by reducing ROS and malondialdehyde concentration... Compared with control group, pretreated groups have shown less Aβ deposition, low expression of beta-site APP-cleaving enzyme 1 and the prevention of tight junction disruption."
(Reinforces reduced Aβ deposition and lipid peroxidation, tying to drusen mitigation in AMD pathogenesis.)
Article Title: Role of amyloid β-peptide in the pathogenesis of age-related macular degeneration
Publication: BMJ Open Ophthalmology
Link: https://bmjophth.bmj.com/content/6/1/e000774

Bioavailability Blend: (Proprietary Formula) 34.5 mg

 Vitamin B13: Phosphatides 50% (Helianthus annua)

 EGb 761 (Ginkgo biloba) (24% Flavone Glycosides, 6% Lactones, <0.0005% Ginkgolic Acid)

 Vitamin B3 (as Niacin) 5 mg 25%

 Miracle Tree 100:1 (Moringa oleifera)

 Licorice Omnipotent (Glycyrrhiza glabra)

 Vinpocetine (Vinca minor)

 Gingerol 10% (Zingiber officinalis)

 Piperine (Piper nigrum)

 Fulvic Acid 

 Humic Acid  

 Spirit Minerals 

Our Bioavailability Blend supplies 21 master ingredients formulated to:

• increase the aqueous solubility of fat-soluble phytonutrients like those in IOP Syntropy

• restore the integrity of the intestinal mucosa, the vascular endothelium, and the blood-brain barrier, which includes the blood-eye barrier, to enhance the selectivity of absorption, transport, and ultimate bioavailability of essential nutrients and phytonutrients to the target tissues and cells.

• stimulate local circulation in the small intestine to increase nutrient absorption into the blood

• increase circulatory perfusion in the eye, brain, and challenging areas of the body to enhance tissue delivery of nutrients

• support and stimulate the sentient, immortal spirit body to regulate and accelerate the body's self-healing processes.

 

The Fibonacci sequence's mathematics seen in living systems and healing processes inspires the Bioavailability Blend's overarching design. This pattern is a blueprint found throughout the nature of the living universe.

This formula also provides excellent support for people with a pterygium, a benign growth on the front of the eye that is akin to a keloid type of scar.

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