Lipid Cleanse supports the restoration of healthy tissue structure and function including the retina.

Soft drusen in the retina produce visual distortion on the Amsler Grid test for monitoring Macular Degeneration.

Drusen are accumulations of waste products of retinal metabolism.

Dissolving and reversal of drusen formation has been reported with long-term use of supplements high in certain nutrients and botanical extracts.

Magnesium L-Threonate crosses the blood-brain and the blood-eye barriers, including the barrier between the blood and the retina.

Magnesium L-Threonate is a specialized nutrient that is not widely available, costing about 30 times as much as Magnesium forms that do not cross the blood-retinal barrier.

However, results are the ultimate metric standard, making the investment in your health and vision cost-effective. 

In practical terms, the most expensive solutions are often the cheap ones, such as commercial supplements which add Magnesium Stearate or Stearic Acid to produce large quantities on high-speed encapsulation machines.

As we describe on another of our websites, Stearates form a biofilm on the supplements and your intestinal mucosa, impairing the bioavailability and absorption of nutrients even from your diet.

Instead, we have developed small-scale, low-speed artisan apothecary systems so you can count on the highest purity, excipient-free, clinically powerful remedies. 

Combined with our lifelong alchemical experience of formulating products and programs for individuals like you, our Functional Formulations™ are incomparable in the marketplace.

Our deeply researched remedies often included as many as two or three dozen synergistic ingredients, producing a more robust entourage effect than typical products based on a single study.

Beyond mere 'supplements' for the body, our sacramental remedies are designed to nourish and activate the causal healing processes of body, mind, and soul.

Each organic pullulan vegicap of Lipid Cleanse (formerly called Drusen Dissolve With Meals) supplies:

Alkaloid:

 Berberine (Coptis chinensis) (radix) 100 mg

“In conclusion, systemic BBR is protective against light‑induced retinal degeneration associated with diminished oxidative stress in the retina. These results suggest that BBR may be a potential therapeutic candidate for retinal degenerative diseases associated with oxidative stress.” Source: Berberine Protects Against Light-Induced Photoreceptor Degeneration in the Mouse Retina

Carotenoid:

 Kelp: Fucoxanthin 85% (Laminaria spp.) 1.2 mg

“These results reveal that hydrogen peroxide activated the expression of drusen‑related proteins in ARPE‑19 cells. However, the increased expressions of Aβ1‑42 and BACE1 were consequently down‑regulated with fucoxanthin pretreatment… Since Aβ‑containing elements are associated with drusen and are considered to be the initial characteristic in retinal tissues with AMD pathogenesis, decreased expression of Aβ suggests it is related to the inhibition of drusen formation.” 

“Altogether, pretreatment with fucoxanthin may protect against premature senescence and cellular dysfunction in retinal cells by oxidative stress in experimental AMD animal and human RPE cell models.” Source: Cytoprotective Potential of Fucoxanthin in Oxidative Stress-Induced Age-Related Macular Degeneration and Retinal Pigment Epithelial Cell Senescence In Vivo and In Vitro

Mineral Factors:

 Selenium (as Methylselenocysteine) 20 mcg 36%

A 2024 review on selenium‑based ocular therapies concludes that “selenium compounds can modulate oxidative stress, inflammation, and apoptosis in ocular tissues,” and highlights their potential in conditions where “oxidative stress plays a central role in pathogenesis,” which explicitly includes AMD in its discussion. Source: Dry age-related macular degeneration: A currently unmet clinical need

 Magnesium (from Magnesium L-Threonate) 2.5 mg 0.6%

Magnesium is nature's Calcium Channel Blocker. Unlike most forms of magnesium, Magnesium L-Threonate crosses the blood-retinal barrier. “At low extracellular Mg²⁺ and high Ca²⁺, the Mg control of mineral growth would be lost so that nodules start proliferating. This proliferation is associated with progression to AMD.” Source: Calcified nodules in retinal drusen are associated with disease progression in age-related macular degeneration

Polyphenols:

 Green Tea: Polyphenols, EGCG 50% (Camelia sinensis) 130 mg

Our findings suggest that GTE and its catechin constituents can serve as potent therapeutic agents to retinal degeneration and support the notion that daily consumption of GTE is beneficial to patients suffering from AMD.” Source: Green tea catechins are potent anti-oxidants that ameliorate sodium iodate-induced retinal degeneration in rats

Quinones:

 Coenzyme Q10 (Ubiquinone) 30 mg

A clinical study of early AMD reported that supplementation with a mitochondrial‑supportive combination “improvement of visual functions and fundus alterations in early age-related macular degeneration… Decrease in drusen-covered area of treated eyes was also statistically significant as compared to placebo when either the most affected eyes (p = 0.045) or the less affected eyes (p = 0.017) were considered.” Source: Improvement of Visual Functions and Fundus Alterations in Early Age-Related Macular Degeneration Treated with a Combination of Acetyl-L-Carnitine, n-3 Fatty Acids, and Coenzyme Q10

 PQQ (Pyrroloquinolinquinone) 3 mg

In primary human RPE from donors with and without AMD, “compounds… to increase mitochondrial biogenesis (Pyrroloquinoline quinone; PQQ)… were used. Mitochondrial function measured after drug treatments showed an AMD‑dependent response; only RPE from donors with AMD showed improvements. All four drugs caused a significant increase in maximal respiration (p < 0.05) compared to untreated controls. Treatment with… PQQ… significantly increased ATP production (p < 0.05).” Source: Improving retinal mitochondrial function as a treatment for age-related macular degeneration

Racetam (Color Vision Nootropic):

 Coluracetam 3 mg

Originally developed as a potential treatment for Alzheimer’s disease and later considered as a treatment for depression and anxiety, coluracetam has become a popular nootropic known for improving mood, increasing motivation, and enhancing color vision. Note that the fatty deposits in the brain in Alzheimer's are nearly identical in composition to drusen in AMD. Source: What Is Coluracetam?

A high consumption of specific nutrients, i.e. β-carotene, lutein and zeaxanthin, copper, folate, magnesium, vitamin A, niacin, vitamin B6, vitamin C, docosahexaenoic acid, and eicosapentaenoic acid, was associated with a lower risk of progression of early to late AMD (high certainty of evidence). Source: What did we learn in 35 years of research on nutrition and supplements for age-related macular degeneration: a systematic review

Terpenoids:

 Ginseng: Ginsenosides 80% (Panax ginseng) 30 mg 

“…the mice treated with ginsenoside Rg3 showed a noticeable reduction in yellow-white precipitates.”

“…the treatment with Rg3 demonstrated a significant ability to restore retinal thickness and reduce the accumulation of drusen deposits beneath the RPE.” Source: Ginsenoside Rg3 Improved Age-Related Macular Degeneration Through Inhibiting ROS-Mediated Mitochondrion-Dependent Apoptosis In Vivo and In Vitro

 Rice: Tocotrienols (Oryza sativa) 30 mg 

“This article explores the scientific foundation supporting the therapeutic efficacy of tocotrienol-rich fraction (TRF) as a viable candidate for slowing AMD progression, based on interventional studies.”

“AMD is characterized by OS, inflammation, dysregulated lipid metabolism, and angiogenesis, all of which TRF purportedly addresses through its potent anti-inflammatory, lipid-lowering, antiangiogenic, and antioxidant properties.” Source: Age-Related Macular Degeneration Pathophysiology and Therapeutic Potential of Tocotrienols: An Update

Vitamin:

 Fat Soluble Vitamin C (L-Ascorbyl Palmitate) 60 mg 33%

From a case report on complete resolution of central soft drusen:
“Supplements prescribed for AMD included ascorbyl palmitate, 450 mg, 4 times per day.” Source: Complete Resolution of Central Soft Drusen without Geographic Atrophy or Choroidal Neovascularization