Heart Health supplies Botanical and Nutritional factors supporting healthy heart rhythm regulation.

This formula is synergistic with Rhythm Restore which contains concentrates of the Botanical combination known in TCM as Wenxin Keli.

Each excipient-free enteric Vegicap supplies:

Nutritional Factors:

 Selenium (as Methylselenocysteine) 100 mcg 143%: Selenium deficiency is linked to cardiomyopathy, heart failure, and coronary heart disease, with Keshan disease successfully prevented and treated by selenium supplementation. Observational studies indicate an inverse relationship between selenium levels and coronary heart disease risk, with one meta-analysis finding that a 50% increase in selenium concentrations corresponded to a 24% lower risk. However, large randomized controlled trials have yielded inconclusive results, possibly due to differences in baseline selenium status among study populations. Selenium’s cardiovascular benefits are thought to be mediated by selenoproteins, which support antioxidant defense, regulate cellular redox balance, participate in thyroid hormone metabolism, control calcium flux important for heart contractions, and modulate inflammation and immune responses—all of which contribute to heart health.

 Magnesium (as Taurate and Ascorbate) 8.2 mg 2%

    Magnesium Taurate 50 mg: Taurine helps lower blood pressure via the renin-angiotensin-aldosterone system (RAAS) and promoting vasodilation. Taurine influences calcium ion (Ca2+) homeostasis in heart cells, improving cardiac contractility and reducing cell damage. Taurine has positive effects in patients with congestive heart failure, including improved functional class, reduced pulmonary crackles, and improved chest film abnormalities. Taurine lowers blood pressure in animal models of hypertension and in some human studies, particularly in prehypertensive individuals. Taurine's antioxidant and anti-inflammatory properties help prevent or slow progression of atherosclerosis. Taurine protects against ischemia-reperfusion injury, a type of damage that can occur during heart attacks or bypass surgery.

    Magnesium Ascorbate 64.2 mg: Doubles Vitamin C absorption from the gut and again into the cytoplasm of cells, resulting in 4 times higher intracellular levels that last twice as long. It is carried by Magnesium which is a beneficial intracellular mineral needed as a cofactor for many enzymes.

 Vitamin C (as Magnesium Ascorbate) 60 mg 100%: Vitamin C supports cardiovascular health by protecting against oxidative stress, inhibiting LDL cholesterol oxidation to help prevent atherosclerosis, and improving endothelial function for better blood pressure regulation. Studies suggest it can lower blood pressure in hypertension, and that low vitamin C levels are linked to higher risks of cardiovascular disease and mortality.

 Vitamin D3 (Cholecalciferol) 1000 IU 167%: Vitamin D may benefit cardiovascular health by improving blood vessel function, reducing inflammation, lowering risk factors such as hypertension and type 2 diabetes, and potentially protecting the heart and blood vessels from damage related to high blood pressure.

 Vitamin E (Mixed Tocopherols) 30 IU 100%: This is the natural full spectrum form found in food, associated with preventive effects, as opposed to typical synthetic supplement forms.

 CoQ10 (Ultra Absorption) 10 mg: Coenzyme Q10 (CoQ10), a vital compound for cellular energy production and a potent antioxidant, declines with age and certain conditions like heart disease. Research suggests it may support heart health by improving symptoms and outcomes in heart failure, lowering blood pressure, aiding recovery after heart attacks, and potentially alleviating statin-related muscle symptoms. Its antioxidant and anti-inflammatory effects may also help protect against the development and progression of cardiovascular disease, though some findings remain inconsistent and larger studies are needed for confirmation.

 Inosine 10 mg: Inosine is a positive inotropic agent, meaning it increases the force of heart muscle contractions. It can dilate coronary blood vessels, improving blood flow. Inosine can reduce damage from ischemia-reperfusion injury due to heart attacks. Inosine has been studied for mitochondrial diseases associated with cardiomyopathy and diabetes. 

Endocrine Support:

 DHEA-S (Dehydroepiandrosterone Sulfate) 5 mg: Low levels of dehydroepiandrosterone sulfate (DHEA-S), the most abundant circulating steroid hormone produced by the adrenal glands, are linked to an increased risk of cardiovascular disease, including coronary heart disease, stroke, and heart failure. Research shows an inverse relationship between DHEA-S levels and these conditions, suggesting that maintaining adequate levels may provide protective effects. Proposed mechanisms include DHEA-S’s anti-inflammatory properties, its ability to improve blood vessel function, and its role in reducing platelet aggregation, all of which may help lower the risk of blood clots, heart attacks, and other cardiovascular complications. A low level of 5 mg per dose is supportive while preventing inhibition of the body's own production.

Enzyme Support:

Lumbrokinase (Lumbricus rubellus) 178,000 LKU 10 mg: Research suggests this fibrinolytic enzyme may help with myocardial infarction, coronary artery disease, and deep vein thrombosis. Lumbrokinase can break down fibrin, a protein that forms blood clots, potentially preventing or dissolving clots that can lead to heart attacks and strokes.  Studies in animals have shown that lumbrokinase can reduce the damage caused by restricted blood flow to the heart muscle during a heart attack (myocardial ischemia) and the subsequent reperfusion (restoration of blood flow).  Some research indicates that lumbrokinase may help prevent the progression of atherosclerosis (plaque buildup in arteries) and other cardiovascular diseases.

Botanical Factors:

Curcumin & Tetrahydrocurcumin (Curcuma longa) 50 mg: These compounds from Turmeric are cardioprotective. 

Curcumin can reduce cardiomyocyte apoptosis, or programmed cell death, after myocardial ischemia-reperfusion injury and in conditions like diabetic cardiomyopathy. Curcumin can inhibit myocardial fibrosis, a process characterized by the excessive deposition of extracellular matrix in the heart, which can impair cardiac function. Curcumin can improve vascular endothelial function, which is crucial for maintaining healthy blood vessels.  

Tetrahydrocurcumin has shown promise in animal models of cardiovascular and metabolic diseases, including myocardial infarction, chronic kidney disease, and diabetic cardiomyopathy, where it has demonstrated potential to attenuate myocardial remodeling, oxidative stress, and apoptosis. Studies suggest that Tetrahydrocurcumin can protect against mitochondrial dysfunction, a factor implicated in various cardiovascular diseases, including ischemic stroke.  

Both curcumin and Tetrahydrocurcumin show potential in ameliorating myocardial ischemia-reperfusion injury by reducing oxidative stress and inflammation, protecting cardiomyocytes, and improving cardiac function. Curcumin and Tetrahydrocurcumin may offer protective effects against diabetic cardiomyopathy by reducing oxidative stress, inflammation, fibrosis, and apoptosis in the heart. Curcumin and THC have been shown to reduce blood pressure and improve vascular responses in some models of hypertension.

MCP (Modified Citrus Pectin) (Citrus spp.) 30 mg: Studies suggest MCP can reduce myocardial fibrosis and inflammation, improve cardiac dysfunction, and inhibit the activity of galectin-3, a protein linked to heart failure and other cardiovascular issues. In animal models, MCP has been shown to prevent isoproterenol-induced cardiac hypertrophy, a condition where the heart muscle thickens. 

Salvianolic Acid B 20% (Salvia miltiorrhiza) 10 mg: Haprotective effects against atherosclerosis by reducing lipid levels, protecting endothelial cells, inhibiting inflammation, and regulating macrophage activity. It can reduce myocardial infarct size, improve cardiac function indices (like LVFS, dp/dt max, and cardiac output), and protect against ischemia/reperfusion injury. It has shown to ameliorate myocardial fibrosis, a condition where scar tissue replaces healthy heart muscle, in models of diabetic cardiomyopathy and other conditions. It is being studied for its potential to protect against various forms of cardiac dysfunction, including that induced by doxorubicin, a chemotherapy drug. It shows potential in treating conditions like cardiac arrest, myocardial ischemia, and cardiac remodeling. 

Astaxanthin (Haematococcus pluvialis) 4 mg: Studies have shown that astaxanthin can reduce LDL cholesterol and total cholesterol levels, while potentially increasing HDL cholesterol in individuals with dyslipidemia and prediabetes. In a study with heart failure patients, astaxanthin was associated with reduced oxidative stress, improved cardiac contractility, and increased exercise tolerance. 

Flavonoids 85% (Crataegus oxyacantha) 20 mg: Hawthorn has a long history of use for heart health. It can increase the force of the heart muscle's contractions (inotropic effect), potentially benefiting patients with heart failure. Imay help prevent cardiac remodeling, the structural changes in the heart associated with various cardiovascular diseases. The flavonoids may help improve blood cholesterol levels, potentially by inhibiting lipid absorption and cholesterol synthesis in the liver and reducing the risk of atherosclerosis.

Reishi 30:1 (Ganoderma lucidum) 20 mg: Studies in animals have shown Reishi extract to reduce blood pressure to levels comparable to pharmaceutical medications in some cases. Reishi may improve blood flow by potentially preventing platelets from clumping together, reducing the risk of blood clots and thrombosis. Reishi's adaptogenic properties can help the body manage stress, which can positively impact heart health by reducing stress-induced blood pressure and inflammation. 

Polyphenols (Camelia sinensis) 10 mg: These bioflavonoids from Green Tea improve the function of the endothelium, the lining of blood vessels, which is critical for regulating blood flow and blood pressure. Some research suggests a link with reduced blood pressure by affecting the renin-angiotensin-aldosterone system. The catechins which are the major component of these polyphenols can improve lipid profiles by reducing LDL cholesterol, and potentially triglycerides.

Bioavailability Factors: 34.5 mg

 Vitamin B13: Phosphatides 50% (Helianthus annua)

 EGb 761 (Ginkgo biloba) (24% Flavone Glycosides, 6% Lactones, <0.0005% Ginkgolic Acid)

 Vitamin B3 (as Niacin) 5 mg 25%

 Miracle Tree 100:1 (Moringa oleifera)

 Licorice Omnipotent (Glycyrrhiza glabra)

 Vinpocetine (Vinca minor)

 Gingerol 10% (Zingiber officinalis)

 Piperine (Piper nigrum)

 Fulvic Acid 

 Humic Acid  

11 Spirit Minerals 

Our Bioavailability Blend supplies 21 master ingredients formulated to:

• increase the aqueous solubility of fat-soluble phytonutrients like those in IOP Syntropy

• restore the integrity of the intestinal mucosa, the vascular endothelium, and the blood-brain barrier, which includes the blood-eye barrier, to enhance the selectivity of absorption, transport, and ultimate bioavailability of essential nutrients and phytonutrients to the target tissues and cells.

• stimulate local circulation in the small intestine to increase nutrient absorption into the blood

• increase circulatory perfusion in the eye, brain, and challenging areas of the body to enhance tissue delivery of nutrients

• support and stimulate the sentient, immortal spirit body to regulate and accelerate the body's self-healing processes.

The Fibonacci sequence's mathematics seen in living systems and healing processes inspires the Bioavailability Blend's overarching design. This pattern is a blueprint found throughout the nature of the living universe.

This formula also provides excellent support for people with a pterygium, a benign growth on the front of the eye that is akin to a keloid type of scar.