IOP Syntropy is formulated to deliver optimal levels of key phytonutrients documented to support regulating and normalizing eye pressure. The suggested dosage range is divided from one to three capsules taken with food throughout the day.

IOP is the scientific acronym for intraocular pressure. It is traditionally measured in millimeters of mercury, abbreviated mmHg. The standard pressure range is 10 to 20 or 21 mmHg, with 15 being the norm.

Pressures consistently above 21 mmHg warrant closer monitoring by an eye care professional. Conversely, an IOP below about 10 mmHg, though less common, can also lead to eye health concerns. Your eye doctor may use different types of tonometry (air puff, applanation, or rebound tonometry) to measure IOP and track any changes over time.

IOP is rarely measured at night, but it usually is a little higher than during the daytime. The primary regulator of nighttime IOP is melatonin, produced by the pineal gland. Melatonin is essential for sleep quality and cleansing the tissues of the central nervous system, including the retina and optic nerve.

IOP Syntropy is synergistic with OcuFlow Bedtime, taken within a half hour of going to bed... or at least turning the lights out to avoid exposure to white and blue light. OcuFlow Bedtime includes enough Melatonin, naturally time-released through the night, to ensure better sleep, cleansing of the CNS through the glymph drainage system discovered just over a decade ago, and supporting healthy nighttime regulation of IOP.

IOP Syntropy is synergistic with WholOmega, with up to four capsules taken together with the heaviest meal of the day. The standardized carotenoid safranal in WholOmega and OcuFlow Bedtime is documented to decrease IOP by about two mmHg.

Take WholOmega separately from IOP Syntropy to avoid competitive inhibition of absorption of the two carotenoids known to help normalize eye pressure: safranal and capsanthin. We focus each Functional Formulation® on a single carotenoid because only one absorption channel in the small intestine is shared by all carotenoids.

If you are also taking OcuFlow Daytime, it is optimal to keep it about two hours apart from IOP Syntropy, since OcuFlow Daytime also supplies safranal. Either remedy can be taken between meals or with a snack if you are sensitive to taking a capsule on an empty stomach. For some people, a capsule floating around in the stomach can trigger discomfort or nausea simply by mechanically stimulating a digestive reaction. A bite of food will prevent that reaction.

Each capsule of IOP Syntropy provides:

Polyphenols:

Also known as bioflavonoids, polyphenols contain multiple phenol ring structures of carbon atoms connected by double bonds. These organic rings have circular fields of delocalized pi electrons that produce a shielding effect similar to a Faraday cage. This leaves an energetic sanctuary in the center of each ring that is an attractive coherence zone for carrying spirit minerals. Polyphenols, other organic ring structures, and pi electron fields produced by living water, essential fatty acids, and DNA are all key loci for the embodiment of the spirit. The sentient, immortal spirit is the substrate and intelligence of consciousness and subconscious processes that regulate and prioritize healing processes. Polyphenols provide many of the healing properties of botanical medicines.

Baicalein (Scutellaria baicalensis) 100 mg 

This polyphenol from the skullcap herb is documented to support a 10% or more significant reduction of IOP. A Baicalein dosage between 100 and 800 mg regulates P13K/AKT signaling. This reduces the production of aqueous humor, the fluid in the eye's anterior chamber. It also increases the outflow of the aqueous. In an animal study, the ocular hypotensive effects of baicalein at concentrations of 4 mg/kg and 40 mg/kg were 9% and 20%, respectively. This research was presented at ARVO in 2015. For a typical 150-pound individual, this translates to a 150 to 1500 mg dosage for a 10-20% IOP drop. Note that a 10-fold increase in dosage is required to double the effect. The most significant increases in therapeutic effectiveness are typically at the lowest dosages. Nevertheless, since a dosage response has been documented for Baicalein, we chose to include double the lower researched dosage in a complete three-capsule-a-day regimen for a projected lowering of IOP of significantly greater than 10%.

Sources:

pmc.ncbi.nlm.nih.gov/articles/PMC8810108/

http://iovs.arvojournals.org/article.aspx?articleid=2268262

Anthocyanidins 25% (Ribes nigrum) 30 mg 

These potent polyphenols from the blackcurrant fruit have been shown to reduce IOP in a clinical study.

Anthocyanidins 25% (Vaccinium myrtillus) 30 mg 

When studied with OPCs (see below), slight IOP reduction has been documented in people with raised eye pressure with these bioflavonoids from bilberry. Researchers also measured increased ocular blood flow. The retina requires more blood flow than any other part of the body since it has the highest metabolism of any tissue.

OPCs (Oligomeric Proanthocyanidins) (Vitis vinifera) (semen) 25 mg 

OPCs produce significant IOP reduction. They are most often obtained from either pine bark or grape seeds, with grapes being more potent. They have also been found to improve retinal and circulatory health.

HMC (Hesperidin Methyl Chalcone) (Citrus aurantium) 165 mg 

This bioflavonoid from bitter orange reduces IOP in animal studies. The dosage range is up to 500 to 1000 mg per day. One of the benefits of HMC is the stabilization of the mast cell membrane.

GBE (Ginkgo Biloba Extract) (Ginkgo biloba) 40 mg 

Ginkgo has been shown to increase ocular blood flow. We include Ginkgo in our Bioavailability Blend, but we've added more to this formula to increase it to a full therapeutic dosage.

Carotenoid:

Carotenoids contain two ring structures linked by a long chain of conjugated double bonds. The pi electrons of this chain resonate with light, protecting against high-energy photons like blue light. The interaction with light frequencies also extends to biocommunication, contributing to the body's photoenergetic regulation. When you enjoy the colors of autumn leaves, you see the effect of carotenoids.

Capsanthin (Capsicum annum) (fructus) 40 mg 

This carotenoid from red peppers supports IOP normalization to a healthy range in one month, even at 40 mg daily. Two or three doses a day provide even greater degrees of normalization.

Diterpene:

Diterpenes have two adjacent hexane rings that share one side of their hexagonal carbon structures.

Forskolin (Coleus forskohlii) 35 mg 

Forskolin is a labdane diterpene from the Indian coleus herb that reduces aqueous humor production. It has antimicrobial as well as anti-inflammatory properties. In some studies, Forskolin can reduce the aqueous humor inflow at 100 to 250 mg daily. 1% Forskolin eye drops can decrease IOP by 4 to 5 mmHg taken two drops thrice daily. 

Endocannabinoid:

PEA (Palmitoylethanolamide) 10 mg 

The endocannabinoid PEA is an endogenous fatty acid amide and lipid modulator. It interacts with peroxisome proliferator-activated receptor alpha (PPAR-α), GPR55, and GPR119 receptors, contributing to its biological activities, including neuroprotection, anti-inflammatory effects, and analgesic properties. PEA supports the regulation of IOP & reduced neuroinflammation. A daily dose would be 300 to 1200 mg, but we have included a homeo-energetic dose to stimulate PEA's regulatory pathways.

Bioavailability Blend 34.5 mg

 Vitamin B13: Phosphatides 50% (Helianthus annua)

 EGb 761 (Ginkgo biloba) (24% Flavone Glycosides, 6% Lactones, <0.0005% Ginkgolic Acid)

 Vitamin B3 (as Niacin) 5 mg 25%

 Miracle Tree 100:1 (Moringa oleifera)

 Licorice Omnipotent (Glycyrrhiza glabra)

 Vinpocetine (Vinca minor)

 Gingerol 10% (Zingiber officinalis)

 Piperine (Piper nigrum)

 Fulvic Acid 

 Humic Acid  

 11 Spirit Minerals

Our Bioavailability Blend supplies 21 master ingredients, including 11 Spirit Minerals, formulated to:

• increase the aqueous solubility of fat-soluble phytonutrients

• support the integrity of the intestinal mucosa, the vascular endothelium, and the blood-brain barrier, and the similar blood-eye barrier, to enhance the selectivity of absorption, transport, and ultimate bioavailability of essential nutrients and phytonutrients to the target tissues and cells.

• stimulate local circulation in the small intestine to increase nutrient absorption into the blood

• increase circulatory perfusion in the eye, brain, and challenging areas of the body to enhance tissue delivery of nutrients

• support and stimulate the sentient, immortal spirit body to regulate and accelerate the body's self-healing processes.

The Fibonacci sequence's mathematics seen in living systems and healing processes inspires the Bioavailability Blend's overarching design. This pattern is a blueprint found throughout the nature of the living universe.

The full effect builds over about one month.

If you take medication for eye pressure, keep seeing your eye doctor, who can measure your pressure as you go.

We are continually developing our solutions and systems, so if you have questions or need support, don't hesitate to fill out the application form, and we'll help you find the solutions that make the most sense for you right now.